Vsi, ki ste opravili gentest za dedno katarakto pri AHT, ste verjetno prejeli tole obvestilo. Jaz ga objavljam tukaj, ker se mi zdi zanimivo tudi za ostale, ki imajo avstralčke in bi mogoče lahko sodelovali v nadaljnji raziskavi v zvezi s tem testom. Kaže namreč, da gentesti le niso tako 100%, predvsem pa je genetika posameznih bolezni še premalo dognana ."Our researchers here at the Animal Health Trust are soon hoping to undertake a follow-up investigation into hereditary cataracts (HC) in the Australian shepherd. Previously, our research team discovered the HC causal HSF4 mutation in this breed, which accounts for the majority of clinically observed cases. However, there seems to be a clinically similar minority form of HC within the breed which isn't caused by the HSF4 mutation.This study will aim to verify the possibility of another HC causal mutation in Australian shepherds, and also attempt to ascertain this mutation.How can you help us?We require samples from; * Clinically affected cataract cases that have been tested clear for the HSF4 mutation. * Older dogs that have been given a clear eye exam over 8 years of age; these will act as ‘controls’.Accompanying copies of eye exams for both affected and control samples are necessary to make them useful towards our research.If you own a dog that qualifies for either category above and wish to contribute a sample, then please contact [email protected] or simply reply to this e-mail.Please include a postal address and how many kits are required with your response."
